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Inarigivir soproxil (SB 9200) is an oral modulator of innate immunity that is believed to act via the activation of the RIG-I and NOD2 pathways
Fancelli D
3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-4-(methylsulfanyl)butanamido]-3-carbamoylpropanamido]-3-methylpentanamido]-4-carbamoylbutanamido]-4-(methylsulfanyl)butanamido]-4-methylpentanamido]-4-methylpentanamido]-4-carboxybutanamido]propanamido]propanamido]-3-carboxypropanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-carboxybutanamido]-5-carbamimidamidopentanoic acid
Formula: C23H24N2O3S
ZX-29 Size:Contact [email protected] for quotation Inarigivir soproxil (SB 9200) isZX 29 is a potent and selective ALK inhibitor with an IC50 of 2. 1 nM, 1. 3 nM and 3. 9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively. ZX 29 is inactive against EGFR. ZX 29 induces apoptosis by inducing endoplasmic reticulum (ER) stress and overcomes cell resistance caused by an ALK mutation. ZX 29 also induces protective autophagy and has antitumor effect. Product information CAS Number: 2254805 62 2 Molecular Weight: 518. 03 Formula:
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