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Development of anaplastic lymphoma kinase (ALK) inhibitors and molecular diagnosis in ALK rearrangement-positive lung cancer
with negligible loss of BRD2 and BRD3
7)8)18(32)22(35)29-16(19(33)21(28)34)12-14-10-9-11-14/h14-18
It shows more than 100-fold selectivity for mTOR relative to PI3Kα
OP-1074 Catalog No.:M13105-10 Development of anaplastic lymphoma kinaseOP 1074 is a pure antiestrogen and a selective ER degrader (PA SERD), shows specific antiestrogenic activity for ER and ER, inhibits 17 estradiol (E2) stimulated transcriptional activity with IC50 of 1. 6 and 3. 2 nM, respectively. Product information CAS Number: 1443752 76 8 Molecular Weight: 457. 56 Formula: C29H31NO4 Chemical Name: (2S) 3 (4 hydroxyphenyl) 4 methyl 2 (4 {2 [(3R) 3 methylpyrrolidin 1 yl]ethoxy}phenyl) 2H chromen 7 ol Smiles:
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