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InChi: InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2
Aconiazide is an anti-tuberculosis prodrug
293(19):7476-7485
Smiles: CC(=O)OCOC(=O)C1=CC2=C(C=C1)C(=O)OC12C2=CC=C(C=C2OC2=CC(=CC=C12)B1OC(C)(C)C(C)(C)O1)OCOC(C)=O
Necrostatin-1 Size:Solid 2 mg InChi: InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2Necrostatin 1 is a potent and selective inhibitor of necroptosis, a mechanism of programmed cell death separate from apoptosis. Necrostatin 1 functions as an allosteric inhibitor of the death domain receptor associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin 1 does not present any perturbation of the Fas TNFR triggered canonical apoptosis cascade. Necrostatin 1 inhibits RIP1