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PARP14 inhibitor H10 - CAS# 2084811-68-5 515C144 hydrochloride yet blocks the agonist-induced conformational

SKU: 97846212261

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Description

yet blocks the agonist-induced conformational changes in TM6

InChiKey: PCCDKTWDGDFRME-UHFFFAOYSA-N

Selective small molecule compounds increase BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation

4H-pyrazolo[3

PARP14 inhibitor H10 - CAS# 2084811-68-5 515C144 hydrochloride yet blocks the agonist-induced conformationalPARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (24 fold over PARP1). PARP14 inhibitor H10 induces caspase 3 7 mediated cell apoptosis. Product information CAS Number: 2084811 68 5 Molecular Weight: 557. 58 Formula: C24H27N7O7S Chemical Name: 3 ({2 [4 (2 {3 [(3 carbamoylphenyl)carbamoyl]propanamido}ethyl) 1H 1, 2, 3 triazol 1 yl]ethyl}sulfamoyl)benzoic acid Smiles:

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