Standard Guide for Performance of Chinese Hamster Ovary Cell/Hypoxanthine Guanine Phosphoribosyl Transferase Gene Mutation Assay Ingestion-build-93833 Note: BS EN 13011 does

Note: BS EN 13011 does not specify standards of performance

class C control function

the form of a filament

This British Standard supersedes BS 5410-1:1977 which is withdrawn

Standard Guide for Performance of Chinese Hamster Ovary Cell/Hypoxanthine Guanine Phosphoribosyl Transferase Gene Mutation Assay Ingestion-build-93833 Note: BS EN 13011 does1. Scope 1. 1 This guide highlights some of the more relevant biological concepts as they are currently understood, and summarizes the critical technical aspects for acceptable bioassay performances as they currently are perceived and practiced. The Chinese hamster ovary cell hypoxanthine guanine phosphoribosyl transferase (CHO HGPRT) assay (1)2 has been widely applied to the toxicological evaluation of industrial and environmental chemicals.