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α-Glucosidase inhibitory effect of Potentilla astracanica and some isoflavones: Inhibition kinetics and mechanistic insights through in vitro and in silico studies
Neuroprotective coumarins from the root of Angelica gigas: structure-activity relationships
3S)-E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for the treatment of cognition/memory disorders
IC50 > 30 μM)
RD162 ipine (hydrochloride) α-Glucosidase inhibitory effect of PotentillaIC50: 30. 9 nM RD162 is an androgen receptor (AR) antagonist. Metastatic prostate cancer is treated with drugs antagonizinf androgen action, but most patients progress to a more aggressive form of the disease named castration resistant prostate cancer, driven by elevated expression of the androgen receptor (AR). In vitro: RD162 was optimized from a screen for nonsteroidal antiandrogens retaining activity in the setting of increased androgen receptor
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US$ 2640.00
US$ 2140.00
US$ 2140.00
US$ 2640.00