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DNA cross-link formation in affected cells is a result of the bioactivation of the drug by the enzyme DT diaphorase (NAD(P)H dehydro-genase (quinone)) in the Walker cells which reduces the 4-nitro group of Tretazicar
A large apparent volume of distribution (138
Formula: C9H14N2O6
Molecular Weight: 955
CCR2 antagonist 4 Catalog No.:M24015-C DNA cross-link formation in affectedCCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP 1 induced chemotaxis with an IC50 of 24 nM. Product information CAS Number: 226226 39 7 Molecular Weight: 439. 86 Formula: C21H21ClF3N3O2 Chemical Name: N [(3R) 1 [(4 chlorophenyl)methyl]pyrrolidin 3 yl] 2 {[3 (trifluoromethyl)phenyl]formamido}acetamide Smiles:
US$ 1462.00
US$ 1280.50