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Chemical Name: (S)-6-(2-(4-cyanophenyl)-2-hydroxy-2-(1-methyl-1H-imidazol-5-yl)ethoxy)-4'-(trifluoromethoxy)-[1
CAS Number: 106083-71-0
and inhibits wet-dog shakes (WDS)-like cold hypersensitivity in mice by 63% at 30 mg/kg
E3 ligase Ligand-Linker Conjugates 32
KB02-SLF Catalog No.:M15097-2 Chemical Name: (S)-6-(2-(4-cyanophenyl)-2-hydroxy-2-(1-methyl-1H-imidazol-5-yl)ethoxy)-4'-(trifluoromethoxy)-[1KB02 SLF is a PROTAC based nuclear FKBP12 degrader (molecular glue). KB02 SLF promotes nuclear FKBP12 degradation by covalently modifying DCAF16 (E3 ligase) and can improve the durability of protein degradation in biological systems. SLF binds ubiquitin E3 ligase ligand KB02 via a linker to form KB02 SLF. Product information CAS Number: 2384184 40 9 Molecular Weight: 949. 52 Formula: C50H65ClN4O12 Chemical Name: (1R) 1 [3 (3 {2 [2 (2 {[1 (2
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