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PS48 - PDK1 Activator. CAS# 1180676-32-7 430 ID-8 (10 μM) stimulates ESCs

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Description

ID-8 (10 μM) stimulates ESCs proliferation in serum-free media for more than 1 month

RKI-1447 is a Type I kinase inhibitor that binds the ATP binding site through interactions with the hinge region and the DFG motif

Therefore another compound

PubMed PMID: 21249704

PS48 - PDK1 Activator. CAS# 1180676-32-7 430 ID-8 (10 μM) stimulates ESCsPS48, CAS No. 1180676 32 7, is a novel PDK1 (phosphoinositide dependent protein kinase 1) activator (Kd = 10. 3 M), which binds to the HM PIF binding pocket rather than the ATP binding site. PS48 has been used to enhance iPSC reprogramming from human epidermal keratinocytes and endothelial cells. Product information CAS Number: 1180676 32 7 Molecular Weight: 286. 75 Formula: C17H15ClO2 Synonym: PS 48 Chemical Name: 5 (4 Chloro phenyl) 3 phenyl pent 2

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