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5-dioxopyrrolidin-1-yl 3-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}propanoate
Moreover EPZ-6438 leads to complete and sustained regression of SMARCB1 mutant MRT xenografts
Accelerated neurite growth from spiral ganglion neurons exposed to the Rho kinase inhibitor H-1152
InChi: InChI=1S/C36H52O11/c1-6-7-19-35(47-34(44)17-16-32(40)41)21-22-36(46-30(35)14-10-25(3)23-33(42)43)20-18-27(5)29(45-36)13-9-24(2)8-12-28(37)26(4)11-15-31(38)39/h8-12
ANI-7 EG1-COOH 5-dioxopyrrolidin-1-yl 3-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}propanoateANI 7 is an activator of aryl hydrocarbon receptor (AhR) pathway. ANI 7 inhibits the growth of multiple cancer cells, and potently and selectively inhibits the growth of MCF 7 breast cancer cells with a GI50 of 0. 56 M. ANI 7 induces CYP1 metabolizing mono oxygenases by activating AhR pathway, and also induces DNA damage, checkpoint Kinase 2 (Chk2) activation, S phase cell cycle arrest, and cell death in sensitive breast cancer cell lines. Product