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in vivo: Efficacy of CuB was tested in vivo using two different orthotopic models of breast cancer
is a potent GPR119 agonist with EC50 of 2
JNJ 28431754
25-13-/t23-
β-Naphthoflavone-CH2-OH Catalog No.:M15296-2 in vivo: Efficacy of CuBNaphthoflavone CH2 OH ( NF CH2 OH) is a ligand for arylhydrocarbon receptor (AhR) E3 ligase. Naphthoflavone CH2 OH can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs (e. g., naphthoflavone JQ1) that recruit the AhR E3 ligase complex by incorporating AhR ligands into chimeric molecules. PROTACs are inducers of ubiquitination mediated degradation of cancer promoting proteins . Product information Molecular Weight: 302. 32