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Echinocystic Acid Inhibits IL-1β-Induced COX-2 and iNOS Expression in Human Osteoarthritis Chondrocytes
2 h) inhibits the phosphorylation of TBK1 in THP-1 cells
ML-7 amplifies the quinocetone-induced cell death through akt and MAPK-mediated apoptosis on HepG2 cell line
InChi: InChI=1S/C15H14O3/c1-9(2)7-8-12-13(16)10-5-3-4-6-11(10)14(17)15(12)18/h3-7
ML380 Catalog No.:M14921-2 Echinocystic Acid Inhibits IL-1β-Induced COX-2ML380 is a potent, subtype selective, and brain penetrant positive allosteric modulator (PAM) of M5 mAChR, with EC50s of 190 and 610 nM for human and rat M5, respectively. ML380 exhibits moderate selectivity versus the M1 and M3 mAChR subtypes. ML380 could increase the affinity of ACh for the M5 mAChR. Product information CAS Number: 1627138 52 6 Molecular Weight: 494. 53 Formula: C23H25F3N4O3S Chemical Name: N ethyl 1 (1H indazole 5 sulfonyl) N {[2
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