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van Diest PJ
7% in the placebo group in the double-blind trial of myelofibrosis
1039/c5mb00161g
but also inhibits DYRK1A potently and a number of other protein kinases in the low micromolar range
FIDAS-5 - CAS# 1391934-98-7 311 van Diest PJFIDAS 5, CAS No. 1391934 98 7, is a potent and orally active methionine S adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2. 1 M. FIDAS 5 effectively competes against S adenosylmethionine (SAM) for MAT2A binding. FIDAS 5 has anticancer activities. Product information CAS Number: 1391934 98 7 Molecular Weight: 261. 72 Formula: C15H13ClFN Chemical Name: FIDAS 5 Smiles: CNC1C=CC( C=C C2=C(F)C=CC=C2Cl)=CC=1 InChiKey: KXVXICBOMOGFMH JXMROGBWSA N
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