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AS-99 15723 Smiles: COC1C=CC(=CC=1)C1OC2=C(C(=O)C=1O)C(O)=CC1OC(C)(C)CCC=12

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Description

Smiles: COC1C=CC(=CC=1)C1OC2=C(C(=O)C=1O)C(O)=CC1OC(C)(C)CCC=12

Formula: C18H18ClN5O3S

BMS-564929 is a subnanomolar AR agonist in vitro

4-b]pyridine-5-carboxylate

AS-99 15723 Smiles: COC1C=CC(=CC=1)C1OC2=C(C(=O)C=1O)C(O)=CC1OC(C)(C)CCC=12AS 99 is a first in class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0. 79 M, Kd= 0. 89 M) with anti leukemic activity. AS 99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo. Product information CAS Number: 2323623 93 2 Molecular Weight: 593. 68 Formula: C27H30F3N5O3S2 Chemical Name:

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