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Trovafloxacin mesylate Size:Contact [email protected] for quotation Glycogen synthase kinase-3β inhibition ameliorates

SKU: 43648866575

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Description

Glycogen synthase kinase-3β inhibition ameliorates cardiac parasympathetic dysfunction in type 1 diabetic Akita mice

Formula: C131H222N44O41

InChiKey: ULWCDKMLERRCJA-UHFFFAOYSA-N

Intradermal injection of compound 48/80 (50 μg in 50 μL saline) resulted in a clear wheal and flare reaction over the 60 min observation period

Trovafloxacin mesylate Size:Contact [email protected] for quotation Glycogen synthase kinase-3β inhibition amelioratesTrovafloxacin mesylate is a broad spectrum quinolone antibiotic with potent activity against Gram positive, Gram negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 M for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2.

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