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The tumor inhibitor and antiangiogenic agent withaferin A targets the intermediate filament protein vimentin
InChi: InChI=1S/C28H35N5O5/c29-21(16-19-10-12-20(34)13-11-19)27(37)33-15-5-9-24(33)26(36)31-22(17-18-6-2-1-3-7-18)28(38)32-14-4-8-23(32)25(30)35/h1-3
this effect is much less pronounced for amphethinile
InChiKey: QBUIDYLGKMWNEA-UHFFFAOYSA-O
L-Sepiapterin Size:Contact [email protected] for quotation The tumor inhibitor and antiangiogenicL Sepiapterin (Sepiapterin) is a precursor of the endothelial nitric oxide synthase (eNOS) cofactor tetrahydrobiopterin (BH4). L Sepiapterin improves endothelial dysfunction in small mesenteric arteries from db db mice, and induces angiogenesis. L Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down regulation of p70S6K dependent VEGFR 2 expression. Product information CAS Number: 17094 01 8 Molecular Weight: 237. 22