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Dahring TK
Philos Trans R Soc Lond B Biol Sci
InChi: InChI=1S/C18H22N2S
Smiles: CC1=CC(=CC=C1OC1C=CN2N=CN=C2C=1)NC1=NC=NC2=CC=C(C=C21)NC1=NC(C)(C)CO1
TAK-901 Size:Solid 2 mg Dahring TKTAK 901 is a small molecule inhibitor of the serine threonine kinase Aurora B with potential antineoplastic activity. Aurora B kinase inhibitor TAK 901 binds to and inhibits the activity of Aurora B, which may result in a decrease in the proliferation of tumor cells that overexpress Aurora B. Aurora B is a positive regulator of mitosis that functions in the attachment of the mitotic spindle to the centromere; the segregation of sister chromatids to