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PubMed Central PMCID: PMC4353377
Kalgutkar AS
Li/c16-9-5-8(15(24)25)12(6-10(9)17)19-14(23)11-1-2-13(21-20-11)22-4-3-18-7-22
BG45 was used at 10 µM final concentration in various in vitro assays
Lenvatinib - CAS# 417716-92-8 Catalog No.:M8564-10 PubMed Central PMCID: PMC4353377Lenvatinib, also known as E7080, is a synthetic, orally available inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR FLK 1) tyrosine kinase with potential antineoplastic activity. E7080 blocks VEGFR2 activation by VEGF, resulting in inhibition of the VEGF receptor signal transduction pathway, decreased vascular endothelial cell migration and proliferation, and vascular endothelial cell apoptosis. Product information
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