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Epub 2014 Dec 11
Garcia-Saez I
PubMed PMID: 25241015
It prevents palmitylation of Wnt proteins by Porcupine (a membrane-bound O-acyltransferase)
Varenicline - CAS# 249296-44-4 60026 Epub 2014 Dec 11Varenicline, CAS No. 249296 44 4, is a nicotinic receptor partial agonistit stimulates nicotine receptors more weakly than nicotine itself does. In this respect it is similar to cytisine and different from the nicotinic antagonist, bupropion, and nicotine replacement therapies (NRTs) like nicotine patches and nicotine gum. Varenicline displays full agonism on 7 nicotinic acetylcholine receptors and is a partial agonist on the 42, 34, and 62 subtypes.