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Smiles: CC1=NN(C(=O)C1=NNC1=CC=CC=C1OCC)C1=NC(=CS1)C1C=CC=CC=1
RGFP966 was used at 10 µM final concentration in various in vitro assays
and metabolism
thereby interfering with a key step in the autophagic process
OG-L002 - LSD1 Inhibitor. CAS# 1357302-64-7 60281 Smiles: CC1=NN(C(=O)C1=NNC1=CC=CC=C1OCC)C1=NC(=CS1)C1C=CC=CC=1OG L002, CAS No. 1357302 64 7, is a highly potent and specific inhibitor of Lysine Specific Demethylase 1 (LSD1). It inhibits LSD1 in biochemical assay with an IC50 ~20 nM, and has moderate inhibitory activity against monoamine oxidases MAO A and MAO B with IC50 ~1. 38 M and 0. 72M respectively. It potently repressed herpes simplex virus (HSV) IE gene expression, genome replication, and reactivation from latency. OG L002 suppressed primary lytic
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