CEP-32496 Hydrochloride - CAS# 1227678-26-3 entin enacarbil GSK-2334470

Name: CEP-32496 Hydrochloride - CAS# 1227678-26-3 entin enacarbil GSK-2334470
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SKU: 6389623446
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Description

GSK-2334470

Makowski K

Niswender CM

GJ103 sodium salt is water soluble

CEP-32496 Hydrochloride - CAS# 1227678-26-3 entin enacarbil GSK-2334470Agerafenib, also known as RXDX 105, CEP 32496 and AC013773, is an orally available v raf murine sarcoma viral oncogene homolog B1 (B raf) serine threonine protein kinase inhibitor with potential antineoplastic activity. CEP 32496 specifically and selectively inhibits the activity of the mutated form (V600E) of B raf kinase. This inhibits the activation of the RAF mitogen activated protein kinase kinase (MEK) extracellular signal related kinase (ERK)

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