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14)7-3-1-2-6(4-7)5-8-9(16)15-10(17)18-8/h1-5H
PU-H71 leads to a proteasome-mediated reduction in IRAK-1 and TBK1 levels
4 μM) in CX3CR1-expressing CHO-K1 membrane but show no antagonistic activity
which shows that PHT-427 could inhibit both Akt and PDPK1
UK-370106 Size:Contact [email protected] for quotation 14)7-3-1-2-6(4-7)5-8-9(16)15-10(17)18-8/h1-5HUK 370106 is a potent and highly selective MMP 3 (IC50 of 23 nM) and MMP 12 (IC50 of 42 nM) inhibitor with >1200 fold higher potency than MMP 1, MMP 2, MMP 9, and MMP 14, and about 100 fold than MMP 13 and MMP 8. UK 370106 potently inhibits cleavage of [3H] fibronectin by MMP 3 (IC50 of 320 nM) and has little effect on keratinocyte migration in vitro. Product information CAS Number: 230961 21 4 Molecular Weight: 572. 73 Formula: C35H44N2O5 Chemical